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Differential transcriptional profiles identify microglial- and macrophage-specific gene markers expressed during virus-induced neuroinflammation

BACKGROUND: In the healthy central nervous system (CNS), microglia are found in a homeostatic state and peripheral macrophages are absent from the brain. Microglia play key roles in maintaining CNS homeostasis and acting as first responders to infection and inflammation, and peripheral macrophages i...

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Dades bibliogràfiques
Publicat a:J Neuroinflammation
Autors principals: DePaula-Silva, Ana Beatriz, Gorbea, Carlos, Doty, Daniel J., Libbey, Jane E., Sanchez, John Michael S., Hanak, Tyler J., Cazalla, Demián, Fujinami, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642742/
https://ncbi.nlm.nih.gov/pubmed/31325960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1545-x
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