Differential transcriptional profiles identify microglial- and macrophage-specific gene markers expressed during virus-induced neuroinflammation

BACKGROUND: In the healthy central nervous system (CNS), microglia are found in a homeostatic state and peripheral macrophages are absent from the brain. Microglia play key roles in maintaining CNS homeostasis and acting as first responders to infection and inflammation, and peripheral macrophages i...

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Publicado en:J Neuroinflammation
Autores principales: DePaula-Silva, Ana Beatriz, Gorbea, Carlos, Doty, Daniel J., Libbey, Jane E., Sanchez, John Michael S., Hanak, Tyler J., Cazalla, Demián, Fujinami, Robert S.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642742/
https://ncbi.nlm.nih.gov/pubmed/31325960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1545-x
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