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Differential transcriptional profiles identify microglial- and macrophage-specific gene markers expressed during virus-induced neuroinflammation

BACKGROUND: In the healthy central nervous system (CNS), microglia are found in a homeostatic state and peripheral macrophages are absent from the brain. Microglia play key roles in maintaining CNS homeostasis and acting as first responders to infection and inflammation, and peripheral macrophages i...

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Pubblicato in:J Neuroinflammation
Autori principali: DePaula-Silva, Ana Beatriz, Gorbea, Carlos, Doty, Daniel J., Libbey, Jane E., Sanchez, John Michael S., Hanak, Tyler J., Cazalla, Demián, Fujinami, Robert S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642742/
https://ncbi.nlm.nih.gov/pubmed/31325960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1545-x
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