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PB1 and UBA domains of p62 are essential for aggresome-like induced structure formation
ALIS are large, transient, cytosolic aggregates that serve as storage compartments for ubiquitin-tagged defective ribosomal products. We determined the importance of the protein p62 in the formation of ALIS and demonstrated that two domains of p62—PB1 and UBA—are essential for ALIS assembly. Those t...
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| Udgivet i: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6640847/ https://ncbi.nlm.nih.gov/pubmed/29966650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.06.153 |
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