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The UBL domain of PLIC-1 regulates aggresome formation

Defects in protein folding and the proteasomal pathway have been linked with many neurodegenerative diseases. PLIC-1 (protein linking IAP to the cytoskeleton) is a ubiquitin-like protein that binds to the ubiquitin-interacting motif (UIM) of the proteasomal subunit S5a. Here, we show that PLIC-1 als...

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Detalhes bibliográficos
Main Authors: Heir, Renu, Ablasou, Celine, Dumontier, Emilie, Elliott, Meghan, Fagotto-Kaufmann, Christine, Bedford, Fiona K
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794689/
https://ncbi.nlm.nih.gov/pubmed/17082820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400823
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