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PB1 and UBA domains of p62 are essential for aggresome-like induced structure formation

ALIS are large, transient, cytosolic aggregates that serve as storage compartments for ubiquitin-tagged defective ribosomal products. We determined the importance of the protein p62 in the formation of ALIS and demonstrated that two domains of p62—PB1 and UBA—are essential for ALIS assembly. Those t...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Cabe, Maleen, Rademacher, David J., Karlsson, Amelia B., Cherukuri, Srinivas, Bakowska, Joanna C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640847/
https://ncbi.nlm.nih.gov/pubmed/29966650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.06.153
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