Current Approaches and Future Perspectives for Nanobodies in Stroke Diagnostic and Therapy

Antibody-based biologics are the corner stone of modern immunomodulatory therapy. Though highly effective in dampening systemic inflammatory processes, their large size and Fc-fragment mediated effects hamper crossing of the blood brain barrier (BBB). Nanobodies (Nbs) are single domain antibodies de...

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Bibliographische Detailangaben
Veröffentlicht in:Antibodies (Basel)
Hauptverfasser: Jank, Larissa, Pinto-Espinoza, Carolina, Duan, Yinghui, Koch-Nolte, Friedrich, Magnus, Tim, Rissiek, Björn
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640704/
https://ncbi.nlm.nih.gov/pubmed/31544811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib8010005
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