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Nanobodies and Nanobody-Based Human Heavy Chain Antibodies As Antitumor Therapeutics
Monoclonal antibodies have revolutionized cancer therapy. However, delivery to tumor cells in vivo is hampered by the large size (150 kDa) of conventional antibodies. The minimal target recognition module of a conventional antibody is composed of two non-covalently associated variable domains (VH an...
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| Published in: | Front Immunol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5702627/ https://ncbi.nlm.nih.gov/pubmed/29213270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01603 |
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