The Cornelia de Lange Syndrome-associated factor NIPBL interacts with BRD4 ET domain for transcription control of a common set of genes

Mutations in NIPBL are the major cause of Cornelia de Lange Syndrome (CdLS). NIPBL is the cohesin-loading factor and has recently been associated with the BET (bromodomains and extra-terminal (ET) domain) proteins BRD2 and BRD4. Related to this, a CdLS-like phenotype has been described associated to...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Luna-Peláez, Noelia, March-Díaz, Rosana, Ceballos-Chávez, María, Guerrero-Martínez, Jose A., Grazioli, Paolo, García-Gutiérrez, Pablo, Vaccari, Thomas, Massa, Valentina, Reyes, Jose C., García-Domínguez, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639259/
https://ncbi.nlm.nih.gov/pubmed/31320616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1792-x
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