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CRISPR-Cas9 genome engineering of primary CD4(+) T cells for the interrogation of HIV-host factor interactions
CRISPR-Cas9 gene-editing strategies have revolutionized our ability to engineer the human genome for robust functional interrogation of complex biological processes. We have recently adapted this technology for use in primary human CD4(+) T cells to create a high-throughput platform for analyzing th...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Protoc |
|---|---|
| Prif Awduron: | , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6637941/ https://ncbi.nlm.nih.gov/pubmed/30559373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-018-0069-7 |
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