Pooled library screening with multiplexed Cpf1 library

Capitalizing on the inherent multiplexing capability of AsCpf1, we developed a multiplexed, high-throughput screening strategy that minimizes library size without sacrificing gene targeting efficiency. We demonstrated that AsCpf1 can be used for functional genomics screenings and that an AsCpf1-base...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Liu, Jintan, Srinivasan, Sanjana, Li, Chieh-Yuan, Ho, I-Lin, Rose, Johnathon, Shaheen, MennatAllah, Wang, Gang, Yao, Wantong, Deem, Angela, Bristow, Chris, Hart, Traver, Draetta, Giulio
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637147/
https://ncbi.nlm.nih.gov/pubmed/31316073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10963-x
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