Three-Component Repurposed Technology for Enhanced Expression: Highly Accumulable Transcriptional Activators via Branched Tag Arrays

In the past few years, several types of artificial transcriptional activator, based on CRISPR-Cas9, have been developed and refined. Of these, in synergistic activation mediator and SunTag systems, the effector proteins, expressed in trans, can be recruited to the target sites via the MS2 RNA-bindin...

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Detalhes bibliográficos
Publicado no:CRISPR J
Main Authors: Kunii, Atsushi, Hara, Yoshihiro, Takenaga, Mitsumasa, Hattori, Naoko, Fukazawa, Takuya, Ushijima, Toshikazu, Yamamoto, Takashi, Sakuma, Tetsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636879/
https://ncbi.nlm.nih.gov/pubmed/31021277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/crispr.2018.0009
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