Three-Component Repurposed Technology for Enhanced Expression: Highly Accumulable Transcriptional Activators via Branched Tag Arrays

In the past few years, several types of artificial transcriptional activator, based on CRISPR-Cas9, have been developed and refined. Of these, in synergistic activation mediator and SunTag systems, the effector proteins, expressed in trans, can be recruited to the target sites via the MS2 RNA-bindin...

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Podrobná bibliografie
Vydáno v:CRISPR J
Hlavní autoři: Kunii, Atsushi, Hara, Yoshihiro, Takenaga, Mitsumasa, Hattori, Naoko, Fukazawa, Takuya, Ushijima, Toshikazu, Yamamoto, Takashi, Sakuma, Tetsushi
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636879/
https://ncbi.nlm.nih.gov/pubmed/31021277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/crispr.2018.0009
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