Three-Component Repurposed Technology for Enhanced Expression: Highly Accumulable Transcriptional Activators via Branched Tag Arrays

In the past few years, several types of artificial transcriptional activator, based on CRISPR-Cas9, have been developed and refined. Of these, in synergistic activation mediator and SunTag systems, the effector proteins, expressed in trans, can be recruited to the target sites via the MS2 RNA-bindin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:CRISPR J
Hauptverfasser: Kunii, Atsushi, Hara, Yoshihiro, Takenaga, Mitsumasa, Hattori, Naoko, Fukazawa, Takuya, Ushijima, Toshikazu, Yamamoto, Takashi, Sakuma, Tetsushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc., publishers 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636879/
https://ncbi.nlm.nih.gov/pubmed/31021277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/crispr.2018.0009
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