Circadian protein BMAL1 promotes breast cancer cell invasion and metastasis by up-regulating matrix metalloproteinase9 expression

BACKGROUND: Metastasis is an important factor in the poor prognosis of breast cancer. As an important core clock protein, brain and muscle arnt-like 1 (BMAL1) is closely related to tumorigenesis. However, the molecular mechanisms that mediate the role of BMAL1 in invasion and metastasis remain large...

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Bibliografske podrobnosti
izdano v:Cancer Cell Int
Main Authors: Wang, Jian, Li, Shujing, Li, Xiahui, Li, Bowen, Li, Yanan, Xia, Kangkai, Yang, Yuxi, Aman, Sattout, Wang, Miao, Wu, Huijian
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Primary Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636133/
https://ncbi.nlm.nih.gov/pubmed/31346317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0902-2
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