SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling

SYNJ2BP plays an important role in breast cancer metastasis. However, the molecular mechanism associated with the function of SYNJ2BP in metastasis remains unclear. In this study, we investigated the role of SYNJ2BP in tumor metastasis and established the associated underlying mechanism. Over-expres...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Miao, Wu, Huijian, Li, Shujing, Xu, Zhaowei, Li, Xiahui, Yang, Yangyang, Li, Bowen, Li, Yanan, Guo, Jing, Chen, Huan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685702/
https://ncbi.nlm.nih.gov/pubmed/29163781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21058
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