SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling

SYNJ2BP plays an important role in breast cancer metastasis. However, the molecular mechanism associated with the function of SYNJ2BP in metastasis remains unclear. In this study, we investigated the role of SYNJ2BP in tumor metastasis and established the associated underlying mechanism. Over-expres...

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Udgivet i:Oncotarget
Main Authors: Wang, Miao, Wu, Huijian, Li, Shujing, Xu, Zhaowei, Li, Xiahui, Yang, Yangyang, Li, Bowen, Li, Yanan, Guo, Jing, Chen, Huan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685702/
https://ncbi.nlm.nih.gov/pubmed/29163781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21058
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