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Synaptic Regulation by OPRM1 Variants in Reward Neurocircuitry
Mu-opioid receptors (MORs) are the primary site of action of opioid drugs, both licit and illicit. Susceptibility to opioid addiction is associated with variants in the gene encoding the MOR, OPRM1. Varying with ethnicity, ∼25% of humans carry a single nucleotide polymorphism (SNP) in OPRM1 (A118G)....
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6636083/ https://ncbi.nlm.nih.gov/pubmed/31109961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2317-18.2019 |
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