Synaptic Regulation by OPRM1 Variants in Reward Neurocircuitry

Mu-opioid receptors (MORs) are the primary site of action of opioid drugs, both licit and illicit. Susceptibility to opioid addiction is associated with variants in the gene encoding the MOR, OPRM1. Varying with ethnicity, ∼25% of humans carry a single nucleotide polymorphism (SNP) in OPRM1 (A118G)....

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Popova, Dina, Desai, Nidhi, Blendy, Julie A., Pang, Zhiping P.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636083/
https://ncbi.nlm.nih.gov/pubmed/31109961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2317-18.2019
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