Synaptic Regulation by OPRM1 Variants in Reward Neurocircuitry

Mu-opioid receptors (MORs) are the primary site of action of opioid drugs, both licit and illicit. Susceptibility to opioid addiction is associated with variants in the gene encoding the MOR, OPRM1. Varying with ethnicity, ∼25% of humans carry a single nucleotide polymorphism (SNP) in OPRM1 (A118G)....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Popova, Dina, Desai, Nidhi, Blendy, Julie A., Pang, Zhiping P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2019
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636083/
https://ncbi.nlm.nih.gov/pubmed/31109961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2317-18.2019
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