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Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon

Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a major public health concern. In vitro persistence is known to develop through interferon gamma (IFN-γ) induction of indoleamine 2,3-dioxygenase (IDO), which catabolizes tryptophan, an essential amino acid...

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Библиографические подробности
Опубликовано в: :mBio
Главные авторы: Somboonna, Naraporn, Ziklo, Noa, Ferrin, Thomas E., Hyuk Suh, Jung, Dean, Deborah
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635532/
https://ncbi.nlm.nih.gov/pubmed/31311884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01464-19
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