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Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon

Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a major public health concern. In vitro persistence is known to develop through interferon gamma (IFN-γ) induction of indoleamine 2,3-dioxygenase (IDO), which catabolizes tryptophan, an essential amino acid...

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Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Somboonna, Naraporn, Ziklo, Noa, Ferrin, Thomas E., Hyuk Suh, Jung, Dean, Deborah
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635532/
https://ncbi.nlm.nih.gov/pubmed/31311884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01464-19
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