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Tryptophan Operon Diversity Reveals Evolutionary Trends among Geographically Disparate Chlamydia trachomatis Ocular and Urogenital Strains Affecting Tryptophan Repressor and Synthase Function

The obligate intracellular pathogen Chlamydia trachomatis (Ct) is the leading cause of bacterial sexually transmitted infections and blindness globally. To date, Ct urogenital strains are considered tryptophan prototrophs, utilizing indole for tryptophan synthesis within a closed-conformation tetram...

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Publicado en:mBio
Main Authors: Bommana, Sankhya, Somboonna, Naraporn, Richards, Gracie, Tarazkar, Maryam, Dean, Deborah
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262981/
https://ncbi.nlm.nih.gov/pubmed/33975934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00605-21
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