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Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon

Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a major public health concern. In vitro persistence is known to develop through interferon gamma (IFN-γ) induction of indoleamine 2,3-dioxygenase (IDO), which catabolizes tryptophan, an essential amino acid...

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Bibliografische gegevens
Gepubliceerd in:mBio
Hoofdauteurs: Somboonna, Naraporn, Ziklo, Noa, Ferrin, Thomas E., Hyuk Suh, Jung, Dean, Deborah
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635532/
https://ncbi.nlm.nih.gov/pubmed/31311884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01464-19
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