Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases

During infection, the fungal pathogen Aspergillus fumigatus forms biofilms that enhance its resistance to antimicrobials and host defenses. An integral component of the biofilm matrix is galactosaminogalactan (GAG), a cationic polymer of α-1,4-linked galactose and partially deacetylated N-acetylgala...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Le Mauff, François, Bamford, Natalie C., Alnabelseya, Noor, Zhang, Yongzhen, Baker, Perrin, Robinson, Howard, Codée, Jeroen D. C., Howell, P. Lynne, Sheppard, Donald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635436/
https://ncbi.nlm.nih.gov/pubmed/31167793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008511
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