Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases

During infection, the fungal pathogen Aspergillus fumigatus forms biofilms that enhance its resistance to antimicrobials and host defenses. An integral component of the biofilm matrix is galactosaminogalactan (GAG), a cationic polymer of α-1,4-linked galactose and partially deacetylated N-acetylgala...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Le Mauff, François, Bamford, Natalie C., Alnabelseya, Noor, Zhang, Yongzhen, Baker, Perrin, Robinson, Howard, Codée, Jeroen D. C., Howell, P. Lynne, Sheppard, Donald C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Microbiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635436/
https://ncbi.nlm.nih.gov/pubmed/31167793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008511
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