PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms

Poly-β(1,6)-N-acetyl-D-glucosamine (PNAG) is a major biofilm component of many pathogenic bacteria. The production, modification, and export of PNAG in Escherichia coli and Bordetella species require the protein products encoded by the pgaABCD operon. PgaB is a two-domain periplasmic protein that co...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Little, Dustin J., Pfoh, Roland, Le Mauff, François, Bamford, Natalie C., Notte, Christina, Baker, Perrin, Guragain, Manita, Robinson, Howard, Pier, Gerald B., Nitz, Mark, Deora, Rajendar, Sheppard, Donald C., Howell, P. Lynne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933820/
https://ncbi.nlm.nih.gov/pubmed/29684093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006998
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