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Combining in situ proteolysis and mass spectrometry to crystallize Escherichia coli PgaB

The periplasmic poly-β-1,6-N-acetyl-d-glucosamine (PNAG) de-N-acetylase PgaB from Escherichia coli was overexpressed and purified, but was recalcitrant to crystallization. Use of the in situ proteolysis technique produced crystals of PgaB, but these crystals could not be optimized for diffraction st...

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Detaylı Bibliyografya
Asıl Yazarlar: Little, Dustin J., Whitney, John C., Robinson, Howard, Yip, Patrick, Nitz, Mark, Howell, P. Lynne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388937/
https://ncbi.nlm.nih.gov/pubmed/22750880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112022075
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