Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms

Bacterial biofilms present a significant medical challenge because they are recalcitrant to current therapeutic regimes. A key component of biofilm formation in the opportunistic human pathogen Pseudomonas aeruginosa is the biosynthesis of the exopolysaccharides Pel and Psl, which are involved in th...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Baker, Perrin, Hill, Preston J., Snarr, Brendan D., Alnabelseya, Noor, Pestrak, Matthew J., Lee, Mark J., Jennings, Laura K., Tam, John, Melnyk, Roman A., Parsek, Matthew R., Sheppard, Donald C., Wozniak, Daniel J., Howell, P. Lynne
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928890/
https://ncbi.nlm.nih.gov/pubmed/27386527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501632
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