Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms

Bacterial biofilms present a significant medical challenge because they are recalcitrant to current therapeutic regimes. A key component of biofilm formation in the opportunistic human pathogen Pseudomonas aeruginosa is the biosynthesis of the exopolysaccharides Pel and Psl, which are involved in th...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Baker, Perrin, Hill, Preston J., Snarr, Brendan D., Alnabelseya, Noor, Pestrak, Matthew J., Lee, Mark J., Jennings, Laura K., Tam, John, Melnyk, Roman A., Parsek, Matthew R., Sheppard, Donald C., Wozniak, Daniel J., Howell, P. Lynne
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928890/
https://ncbi.nlm.nih.gov/pubmed/27386527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501632
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