Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms

Bacterial biofilms present a significant medical challenge because they are recalcitrant to current therapeutic regimes. A key component of biofilm formation in the opportunistic human pathogen Pseudomonas aeruginosa is the biosynthesis of the exopolysaccharides Pel and Psl, which are involved in th...

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Опубликовано в: :Sci Adv
Главные авторы: Baker, Perrin, Hill, Preston J., Snarr, Brendan D., Alnabelseya, Noor, Pestrak, Matthew J., Lee, Mark J., Jennings, Laura K., Tam, John, Melnyk, Roman A., Parsek, Matthew R., Sheppard, Donald C., Wozniak, Daniel J., Howell, P. Lynne
Формат: Artigo
Язык:Inglês
Опубликовано: American Association for the Advancement of Science 2016
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928890/
https://ncbi.nlm.nih.gov/pubmed/27386527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501632
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