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Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation

Xist RNA, the master regulator of X chromosome inactivation, acts in cis to induce chromosome-wide silencing. Whilst recent studies have defined candidate silencing factors, their relative contribution to repressing different genes, and their relationship with one another is poorly understood. Here...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Nesterova, Tatyana B., Wei, Guifeng, Coker, Heather, Pintacuda, Greta, Bowness, Joseph S., Zhang, Tianyi, Almeida, Mafalda, Bloechl, Bianca, Moindrot, Benoit, Carter, Emma J., Alvarez Rodrigo, Ines, Pan, Qi, Bi, Ying, Song, Chun-Xiao, Brockdorff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635394/
https://ncbi.nlm.nih.gov/pubmed/31311937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11171-3
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