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Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation

Xist RNA, the master regulator of X chromosome inactivation, acts in cis to induce chromosome-wide silencing. Whilst recent studies have defined candidate silencing factors, their relative contribution to repressing different genes, and their relationship with one another is poorly understood. Here...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Nesterova, Tatyana B., Wei, Guifeng, Coker, Heather, Pintacuda, Greta, Bowness, Joseph S., Zhang, Tianyi, Almeida, Mafalda, Bloechl, Bianca, Moindrot, Benoit, Carter, Emma J., Alvarez Rodrigo, Ines, Pan, Qi, Bi, Ying, Song, Chun-Xiao, Brockdorff, Neil
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635394/
https://ncbi.nlm.nih.gov/pubmed/31311937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11171-3
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