Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation

Xist RNA, the master regulator of X chromosome inactivation, acts in cis to induce chromosome-wide silencing. Whilst recent studies have defined candidate silencing factors, their relative contribution to repressing different genes, and their relationship with one another is poorly understood. Here...

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Pubblicato in:Nat Commun
Autori principali: Nesterova, Tatyana B., Wei, Guifeng, Coker, Heather, Pintacuda, Greta, Bowness, Joseph S., Zhang, Tianyi, Almeida, Mafalda, Bloechl, Bianca, Moindrot, Benoit, Carter, Emma J., Alvarez Rodrigo, Ines, Pan, Qi, Bi, Ying, Song, Chun-Xiao, Brockdorff, Neil
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635394/
https://ncbi.nlm.nih.gov/pubmed/31311937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11171-3
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