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Glucose, adrenaline and palmitate antagonistically regulate insulin and glucagon secretion in human pseudoislets
Isolated human islets do not always meet the quality standards required for transplant survival and reliable functional in vitro studies. The formation of pseudoislets, i.e. the reaggregation of a defined number of islet cells after dissociation, improves insulin secretion. We present a simple metho...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6635387/ https://ncbi.nlm.nih.gov/pubmed/31311971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46545-6 |
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