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Advances in Structural and Single-Molecule Methods for Investigating DNA Lesion Bypass and Repair Polymerases

Innovative advances in X-ray crystallography and single-molecule biophysics have yielded unprecedented insight into the mechanisms of DNA lesion bypass and damage repair. Time-dependent X-ray crystallography has been successfully applied to view the bypass of 8-oxo-7,8-dihydro-2′-deoxyguanine (8-oxo...

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Publicat a:Chem Res Toxicol
Autors principals: Raper, Austin T., Reed, Andrew J., Gadkari, Varun V., Suo, Zucai
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634979/
https://ncbi.nlm.nih.gov/pubmed/28092942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00342
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