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Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling

Proliferating cell nuclear antigen (PCNA) is a trimeric ring-shaped clamp protein that encircles DNA and interacts with many proteins involved in DNA replication and repair. Despite extensive structural work to characterize the monomeric, dimeric, and trimeric forms of PCNA alone and in complex with...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gadkari, Varun V, Harvey, Sophie R, Raper, Austin T, Chu, Wen-Ting, Wang, Jin, Wysocki, Vicki H, Suo, Zucai
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888646/
https://ncbi.nlm.nih.gov/pubmed/29529283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky125
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