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Binding-Induced Conformational Changes Involved in Sliding Clamp PCNA and DNA Polymerase DPO4

Cooperation between DNA polymerases and DNA sliding clamp proteins is essential for DNA replication and repair. However, it is still challenging to clarify the binding mechanism and the movements of Y-family DNA polymerase IV (DPO4) on the proliferating cell nuclear antigen (PCNA) ring. Here we deve...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Chu, Wen-Ting, Suo, Zucai, Wang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229285/
https://ncbi.nlm.nih.gov/pubmed/32422591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101117
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