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Motion of a DNA Sliding Clamp Observed by Single Molecule Fluorescence Spectroscopy

DNA sliding clamps attach to polymerases and slide along DNA to allow rapid, processive replication of DNA. These clamps contain many positively charged residues that could curtail the sliding due to attractive interactions with the negatively charged DNA. By single-molecule spectroscopy we have obs...

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Detalhes bibliográficos
Principais autores: Laurence, Ted A., Kwon, Youngeun, Johnson, Aaron, Hollars, Christopher W., O'Donnell, Mike, Camarero, Julio A., Barsky, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516983/
https://ncbi.nlm.nih.gov/pubmed/18556658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800174200
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