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Single-Molecule Investigation of Response to Oxidative DNA Damage by a Y-Family DNA Polymerase

Y-family DNA polymerases are known to bypass DNA lesions in vitro and in vivo and rescue stalled DNA replication machinery. Dpo4, a well-characterized model Y-family DNA polymerase, is known to catalyze translesion synthesis across a variety of DNA lesions including 8-oxo-7,8-dihydro-2′-deoxyguanine...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Raper, Austin T., Gadkari, Varun V., Maxwell, Brian A., Suo, Zucai
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026495/
https://ncbi.nlm.nih.gov/pubmed/27002236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00166
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