RBPJκ-Dependent Signaling Is Essential for Long-Term Maintenance of Neural Stem Cells in the Adult Hippocampus

The generation of new neurons from neural stem cells in the adult hippocampal dentate gyrus contributes to learning and mood regulation. To sustain hippocampal neurogenesis throughout life, maintenance of the neural stem cell pool has to be tightly controlled. We found that the Notch/RBPJκ-signaling...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Ehm, Oliver, Göritz, Christian, Covic, Marcela, Schäffner, Iris, Schwarz, Tobias J., Karaca, Esra, Kempkes, Bettina, Kremmer, Elisabeth, Pfrieger, Frank W., Espinosa, Lluis, Bigas, Anna, Giachino, Claudio, Taylor, Verdon, Frisén, Jonas, Lie, D. Chichung
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2010
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633732/
https://ncbi.nlm.nih.gov/pubmed/20943920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1567-10.2010
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