RBPJκ-Dependent Signaling Is Essential for Long-Term Maintenance of Neural Stem Cells in the Adult Hippocampus

The generation of new neurons from neural stem cells in the adult hippocampal dentate gyrus contributes to learning and mood regulation. To sustain hippocampal neurogenesis throughout life, maintenance of the neural stem cell pool has to be tightly controlled. We found that the Notch/RBPJκ-signaling...

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Publicado no:J Neurosci
Main Authors: Ehm, Oliver, Göritz, Christian, Covic, Marcela, Schäffner, Iris, Schwarz, Tobias J., Karaca, Esra, Kempkes, Bettina, Kremmer, Elisabeth, Pfrieger, Frank W., Espinosa, Lluis, Bigas, Anna, Giachino, Claudio, Taylor, Verdon, Frisén, Jonas, Lie, D. Chichung
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633732/
https://ncbi.nlm.nih.gov/pubmed/20943920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1567-10.2010
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