Mitochondrial Dysfunction in Astrocytes Impairs the Generation of Reactive Astrocytes and Enhances Neuronal Cell Death in the Cortex Upon Photothrombotic Lesion

Mitochondria are key organelles in regulating the metabolic state of a cell. In the brain, mitochondrial oxidative metabolism is the prevailing mechanism for neurons to generate ATP. While it is firmly established that neuronal function is highly dependent on mitochondrial metabolism, it is less wel...

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Bibliografski detalji
Izdano u:Front Mol Neurosci
Glavni autori: Fiebig, Christian, Keiner, Silke, Ebert, Birgit, Schäffner, Iris, Jagasia, Ravi, Lie, D. Chichung, Beckervordersandforth, Ruth
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6395449/
https://ncbi.nlm.nih.gov/pubmed/30853890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00040
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