Low Nociceptor GRK2 Prolongs Prostaglandin E(2) Hyperalgesia via Biased cAMP Signaling to Epac/Rap1, Protein Kinase Cε, and MEK/ERK

Hyperexcitability of peripheral nociceptive pathways is often associated with inflammation and is an important mechanism underlying inflammatory pain. Here we describe a completely novel mechanism via which nociceptor G-protein-coupled receptor kinase 2 (GRK2) contributes to regulation of inflammato...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Eijkelkamp, Niels, Wang, Huijing, Garza-Carbajal, Anibal, Willemen, Hanneke L. D. M., Zwartkruis, Fried J., Wood, John N., Dantzer, Robert, Kelley, Keith W., Heijnen, Cobi J., Kavelaars, Annemieke
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633564/
https://ncbi.nlm.nih.gov/pubmed/20861385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3142-10.2010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados