The Death Receptor Antagonist FLIP-L Interacts with Trk and Is Necessary for Neurite Outgrowth Induced by Neurotrophins

FLICE-inhibitory protein (FLIP) is an endogenous inhibitor of the signaling pathway triggered by the activation of death receptors. Here, we reveal a novel biological function for the long form of FLIP (FLIP-L) in neuronal differentiation, which can be dissociated from its antiapoptotic role. We sho...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Moubarak, Rana S., Solé, Carme, Pascual, Marta, Gutierrez, Humberto, Llovera, Marta, Pérez-García, M. José, Gozzelino, Raffaella, Segura, Miguel F., Iglesias-Guimarais, Victoria, Reix, Stéphanie, Soler, Rosa M., Davies, Alun M., Soriano, Eduardo, Yuste, Victor J., Comella, Joan X.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632611/
https://ncbi.nlm.nih.gov/pubmed/20427667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0537-10.2010
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