TNFα induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway

Activation of tumor necrosis factor receptor-1 can trigger survival or apoptosis pathways. In many cellular models, including the neuronal cell model PC12, it has been demonstrated that inhibition of protein synthesis is sufficient to render cells sensitive to apoptosis induced by TNFα. The survival...

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Detalhes bibliográficos
Main Authors: Marques-Fernandez, F, Planells-Ferrer, L, Gozzelino, R, Galenkamp, K MO, Reix, S, Llecha-Cano, N, Lopez-Soriano, J, Yuste, V J, Moubarak, R S, Comella, J X
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734812/
https://ncbi.nlm.nih.gov/pubmed/23412386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.25
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