TNFα induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway

Activation of tumor necrosis factor receptor-1 can trigger survival or apoptosis pathways. In many cellular models, including the neuronal cell model PC12, it has been demonstrated that inhibition of protein synthesis is sufficient to render cells sensitive to apoptosis induced by TNFα. The survival...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Marques-Fernandez, F, Planells-Ferrer, L, Gozzelino, R, Galenkamp, K MO, Reix, S, Llecha-Cano, N, Lopez-Soriano, J, Yuste, V J, Moubarak, R S, Comella, J X
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2013
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734812/
https://ncbi.nlm.nih.gov/pubmed/23412386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.25
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