Cellular Form of Prion Protein Inhibits Reelin-Mediated Shedding of Caspr from the Neuronal Cell Surface to Potentiate Caspr-Mediated Inhibition of Neurite Outgrowth

Extension of axonal and dendritic processes in the CNS is tightly regulated by outgrowth-promoting and -inhibitory cues to assure precision of synaptic connections. We identify a novel role for contactin-associated protein (Caspr) as an inhibitory cue that reduces neurite outgrowth from CNS neurons....

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Bibliographic Details
Published in:J Neurosci
Main Authors: Devanathan, Vasudharani, Jakovcevski, Igor, Santuccione, Antonella, Li, Shen, Lee, Hyun Joon, Peles, Elior, Leshchyns'ka, Iryna, Sytnyk, Vladimir, Schachner, Melitta
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632488/
https://ncbi.nlm.nih.gov/pubmed/20610764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5657-09.2010
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