Clustering of the Neural Cell Adhesion Molecule (NCAM) at the Neuronal Cell Surface Induces Caspase-8- and -3-dependent Changes of the Spectrin Meshwork Required for NCAM-mediated Neurite Outgrowth

Changes in neuronal morphology underlying neuronal differentiation depend on rapid and sustained cytoskeleton rearrangements in the growing neurites. Whereas cell adhesion molecules are well established as regulators of neuronal differentiation, less is known about the signaling mechanisms by which...

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Hlavní autoři: Westphal, Doreen, Sytnyk, Vladimir, Schachner, Melitta, Leshchyns'ka, Iryna
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Neurobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009930/
https://ncbi.nlm.nih.gov/pubmed/20961848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177147
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