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Clustering of the Neural Cell Adhesion Molecule (NCAM) at the Neuronal Cell Surface Induces Caspase-8- and -3-dependent Changes of the Spectrin Meshwork Required for NCAM-mediated Neurite Outgrowth

Changes in neuronal morphology underlying neuronal differentiation depend on rapid and sustained cytoskeleton rearrangements in the growing neurites. Whereas cell adhesion molecules are well established as regulators of neuronal differentiation, less is known about the signaling mechanisms by which...

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Main Authors: Westphal, Doreen, Sytnyk, Vladimir, Schachner, Melitta, Leshchyns'ka, Iryna
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009930/
https://ncbi.nlm.nih.gov/pubmed/20961848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177147
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