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RPTPα is essential for NCAM-mediated p59(fyn) activation and neurite elongation

The neural cell adhesion molecule (NCAM) forms a complex with p59(fyn) kinase and activates it via a mechanism that has remained unknown. We show that the NCAM140 isoform directly interacts with the intracellular domain of the receptor-like protein tyrosine phosphatase RPTPα, a known activator of p5...

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Detalhes bibliográficos
Main Authors: Bodrikov, Vsevolod, Leshchyns'ka, Iryna, Sytnyk, Vladimir, Overvoorde, John, den Hertog, Jeroen, Schachner, Melitta
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171675/
https://ncbi.nlm.nih.gov/pubmed/15623578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405073
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