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TNF-α promotes human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells through downregulating P38-mediated Occludin expression
BACKGROUND: The major limitation of organ transplantation is the shortage of available organs. Xenotransplantation is considered to be an effective way to resolve the problem. Immune rejection is a major hurdle for the successful survival of pig xenografts in primate recipients. Cytokines play impor...
Shranjeno v:
| izdano v: | Cell Commun Signal |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6631523/ https://ncbi.nlm.nih.gov/pubmed/31307477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0386-7 |
| Oznake: |
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