TNFα alters occludin and cerebral endothelial permeability: Role of p38MAPK

Occludin is a key tight junction (TJ) protein in cerebral endothelial cells (CECs) playing an important role in modulating blood-brain barrier (BBB) functions. This protein (65kDa) has been shown to engage in many signaling pathways and phosphorylation by both tyrosine and threonine kinases. Despite...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Ni, Yawen, Teng, Tao, Li, Runting, Simonyi, Agnes, Sun, Grace Y., Lee, James C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295672/
https://ncbi.nlm.nih.gov/pubmed/28170408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170346
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