c-Jun N-terminal kinases differentially regulate TNF- and TLRs-mediated necroptosis through their kinase-dependent and -independent activities

Tumor necrosis factor (TNF) and Toll-like receptor (TLR)3/TLR4 activation trigger necroptotic cell death through downstream signaling complex containing receptor-interacting protein kinase 1 (RIPK1), RIPK3, and pseudokinase mixed lineage kinase-domain-like (MLKL). However, the regulation of necropto...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Cao, Mengtao, Chen, Fei, Xie, Ni, Cao, Meng-Yao, Chen, Pengfei, Lou, Qi, Zhao, Yanli, He, Chen, Zhang, Shuyuan, Song, Xinyang, Sun, Yu, Zhu, Weimin, Mou, Lisha, Luan, Shaodong, Gao, Hanchao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238001/
https://ncbi.nlm.nih.gov/pubmed/30442927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1189-2
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