Cigarette smoke–induced reduction of C1q promotes emphysema

Alteration of innate immune cells in the lungs can promote loss of peripheral tolerance that leads to autoimmune responses in cigarette smokers. Development of autoimmunity in smokers with emphysema is also strongly linked to the expansion of autoreactive T helper (Th) cells expressing interferon γ...

Full description

Saved in:
Bibliographic Details
Published in:JCI Insight
Main Authors: Yuan, Xiaoyi, Chang, Cheng-Yen, You, Ran, Shan, Ming, Gu, Bon Hee, Madison, Matthew C., Diehl, Gretchen, Perusich, Sarah, Song, Li-Zhen, Cornwell, Lorraine, Rossen, Roger D., Wetsel, Rick, Kimal, Rajapakshe, Coarfa, Cristian, Eltzschig, Holger K., Corry, David B., Kheradmand, Farrah
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629245/
https://ncbi.nlm.nih.gov/pubmed/31112138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124317
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items