Cigarette smoke–induced reduction of C1q promotes emphysema

Alteration of innate immune cells in the lungs can promote loss of peripheral tolerance that leads to autoimmune responses in cigarette smokers. Development of autoimmunity in smokers with emphysema is also strongly linked to the expansion of autoreactive T helper (Th) cells expressing interferon γ...

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Enregistré dans:
Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Yuan, Xiaoyi, Chang, Cheng-Yen, You, Ran, Shan, Ming, Gu, Bon Hee, Madison, Matthew C., Diehl, Gretchen, Perusich, Sarah, Song, Li-Zhen, Cornwell, Lorraine, Rossen, Roger D., Wetsel, Rick, Kimal, Rajapakshe, Coarfa, Cristian, Eltzschig, Holger K., Corry, David B., Kheradmand, Farrah
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629245/
https://ncbi.nlm.nih.gov/pubmed/31112138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124317
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